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that evaluated sermorelins effects on GH and IGF-1 levels in 9 young men (22 to 33 years old) and 10 elderly men (60 to 78 years old)

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[DOI] [PubMed] [Google Scholar] 181.Cristante E, McArthur S, Mauro C, et al

This effect was so pronounced that researchers developed PT-141 (bremelanotide) specifically to target it, receiving FDA approval in 2019 as Vyleesi (Clayton et al., 2016)

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The general occurrence of this dehydroalanine-derived post-translational modification thus makes a strong candidate to search by proteomic-based approaches [210] its presence in inactivated enzymes and in other proteins